Abstract Background The natural history of non-metastatic castrate refractory prostate cancer is unknown and treatment options are limited. We present a retrospective review of 13 patients with locally advanced or high risk prostate cancer. initially treated with hormone monotherapy and then treated with prostate radiation after becoming castration refractory. Findings Median PSA resp... https://www.marcelovicente.com/product-category/q10-time-restore-treatment/