BackgroundTick Subolesin and its ortholog in insects and vertebrates. Akirin. have been suggested to play a role in the immune response through regulation of nuclear factor-kappa B (NF-kB)-dependent and independent gene expression via interaction with intermediate proteins that interact with NF-kB and other regulatory proteins. bind DNA or remodel chromatin to regulate gene expression. https://www.chiggate.com/nicabate-clear-patch-stop-smoking-transdermal-drug-delivery-system-nicotine-21mg-7-pack-online/